erythromycin


SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](C(=O)[C@@H]([C@H]([C@]1(C)O)O)C)C)(C)O
InChIKey ULGZDMOVFRHVEP-RWJQBGPGSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 7
Molecular weight (Da) 733.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8IBU

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
motilin MTLR Human Motilin A pKi 4.43 4.43 4.43 ChEMBL
motilin MTLR Human Motilin A pKi 8.35 8.35 8.35 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
motilin MTLR Human Motilin A pIC50 5.5 6.0 6.5 Guide to Pharmacology
motilin MTLR Human Motilin A pEC50 6.0 6.53 7.3 ChEMBL
motilin MTLR Human Motilin A pIC50 7.15 7.26 7.36 ChEMBL
motilin A5A4K8 Rabbit Motilin A pEC50 5.92 5.92 5.92 ChEMBL