CHEMBL409225


SMILES C[C@H](C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O)N1Cc2cc(O)ccc2C[C@H](N)C1=O
InChIKey ACFTTXWQZSBVGL-OREJSRFESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 479.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.8 6.8 6.8 ChEMBL
μ OPRM Human Opioid A pKi 5.57 5.57 5.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pIC50 4.52 4.52 4.52 ChEMBL
μ OPRM Rat Opioid A pIC50 4.68 6.18 7.68 ChEMBL
μ OPRM Human Opioid A pEC50 8.29 8.29 8.29 ChEMBL