CHEMBL4099470


SMILES COc1ccccc1C(=O)N[C@H]1C[C@@](N)(C(=O)O)[C@@H]2[C@@H](C(=O)O)[C@H]12
InChIKey RZEDXUFBIJSIMV-SWKDTAOHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 334.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.63 7.63 7.63 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 8.15 8.15 8.15 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.58 7.58 7.58 ChEMBL