CHEMBL4107906


SMILES CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccccc1)[C@H]1Cc4ccc(F)c5c4[C@@]3(CCN1C)[C@H]2O5
InChIKey LURXKAVKEBVYHH-RHRQCQTHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.03 7.03 7.03 ChEMBL
κ OPRK Human Opioid A pKi 9.72 9.72 9.72 ChEMBL
μ OPRM Human Opioid A pKi 8.36 8.36 8.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.17 7.17 7.17 ChEMBL
κ OPRK Human Opioid A pEC50 7.64 7.64 7.64 ChEMBL
μ OPRM Human Opioid A pEC50 8.1 8.1 8.1 ChEMBL