CHEMBL4114978


SMILES Cc1ccc(-n2nccn2)c(C(=O)N2[C@H]3CC[C@@H]2[C@@H](COc2ccc(F)cn2)C3)c1
InChIKey FNSBFXNNFNCHOW-HHXXYDBFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 5.41 5.41 5.41 ChEMBL
OX1 OX1R Human Orexin A pKi 5.5 5.5 5.5 ChEMBL
OX2 OX2R Human Orexin A pKi 5.29 5.29 5.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database