CHEMBL4117725


SMILES Oc1ccc(CCN(CCc2cccc(O)c2F)CC2CCC2)cc1
InChIKey XZAKPXBVBYAINZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 343.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 5.88 5.88 5.88 ChEMBL
κ OPRK Human Opioid A pKi 8.47 8.47 8.47 ChEMBL
μ OPRM Human Opioid A pKi 6.28 6.28 6.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 7.43 7.43 7.43 ChEMBL