CHEMBL413530


SMILES CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H](CN1CCCC1)c1cccc(N)c1
InChIKey GZGGYQMNFMHDFI-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 405.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 10.23 10.23 10.23 ChEMBL
κ OPRK Guinea pig Opioid A pKd 8.47 8.47 8.47 ChEMBL
δ OPRD Human Opioid A pKi 8.11 8.11 8.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 9.92 9.92 9.92 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 9.77 9.77 9.77 ChEMBL
δ OPRD Human Opioid A pIC50 7.05 7.05 7.05 ChEMBL