CHEMBL4160064


SMILES COc1cccc(-c2ccc3c(c2)CCN(Cc2ccccc2)C3)c1
InChIKey BDECJFBHDUVJRU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 329.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.31 5.31 5.31 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.56 5.56 5.56 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.62 5.62 5.62 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.42 8.42 8.42 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.5 5.5 5.5 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.17 5.17 5.17 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.76 6.76 6.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.13 6.13 6.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database