(S)APOMORPHINE


SMILES CN1CCc2cccc3c2[C@@H]1Cc1ccc(O)c(O)c1-3
InChIKey VMWNQDUVQKEIOC-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 267.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 5.53 5.53 5.53 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 5.44 5.44 5.44 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 8.25 8.25 8.25 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.17 6.17 6.17 ChEMBL