CHEMBL416647


SMILES COc1ccc2c(c1O)[C@]13CCN(C)[C@H](C2)[C@]1(O)Cc1c([nH]c2ccccc12)C3
InChIKey NVKFKYFEFLFZKJ-AGILITTLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 5.54 5.54 5.54 ChEMBL
δ OPRD Human Opioid A pKi 7.66 7.66 7.66 ChEMBL
κ OPRK Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
μ OPRM Human Opioid A pKi 5.73 5.73 5.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database