CHEMBL4212199


SMILES O=S(=O)(NC1CCN(CC(O)COc2ccccc2-c2ccccc2)CC1)c1cccc(Cl)c1
InChIKey JFHVZERFQKQSFW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 500.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database