CHEMBL4238029


SMILES O=S(=O)(c1cccc2ncccc12)N1CCC[C@H]1CCN1CCN(c2cccc3[nH]ccc23)CC1
InChIKey XTHNKXHWYMMNTD-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 489.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database