CHEMBL424128


SMILES NCCc1c[nH]c2ccc(OCCCCCCOc3ccc4[nH]cc(CCN)c4c3)cc12
InChIKey KKDGSWZZEGKXRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 13
Molecular weight (Da) 434.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.3 9.3 9.3 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.34 9.34 9.34 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pEC50 9.22 9.22 9.22 ChEMBL