CHEMBL4248597


SMILES O=S(=O)(c1cccc2ncccc12)N1CCC[C@@H]1CCN1CCN(c2cccc3[nH]ccc23)CC1
InChIKey XTHNKXHWYMMNTD-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 489.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.1 8.1 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database