CHEMBL425069


SMILES COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2ccccc21
InChIKey ADLYXAHODXNVQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.42 7.42 7.42 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.74 5.74 5.74 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.77 6.77 6.77 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.86 7.86 7.86 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database