CHEMBL4294279


SMILES COc1cc2c(cc1O)CN(CCCCNC(=O)c1ccc(O)cc1)CC2
InChIKey HTIHIBRTTCYUMB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 370.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.38 6.38 6.38 ChEMBL