CHEMBL1243395


SMILES FC(F)(F)c1ccc(SC[C@@H](c2c[nH]cn2)C2CCNCC2)cc1
InChIKey HGLGWLWXYRAXPK-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.51 6.51 6.51 ChEMBL
H1 HRH1 Human Histamine A pKi 7.32 7.32 7.32 ChEMBL
H3 HRH3 Human Histamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 7.13 7.13 7.13 ChEMBL