CHEMBL430397


SMILES C[C@H]1C2Cc3ccc(C(=O)NCCCc4ccc5ccccc5c4)cc3[C@@]1(C)CCN2CC1CC1
InChIKey LOUFHRFNYKWWBM-WTBOZYSNSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 466.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.75 7.75 7.75 ChEMBL
κ OPRK Human Opioid A pKi 9.74 9.74 9.74 ChEMBL
μ OPRM Human Opioid A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 8.2 8.2 8.2 ChEMBL
μ OPRM Human Opioid A pIC50 6.5 6.5 6.5 ChEMBL
μ OPRM Human Opioid A pEC50 7.62 7.62 7.62 ChEMBL