CHEMBL430522


SMILES COc1c(C(=O)N[C@H]2CN(Cc3ccccc3)C[C@@H]2C)cc(Br)c2ccccc12
InChIKey ZLQMLDGHTKCIRQ-AOMKIAJQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 452.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.08 5.23 5.38 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.23 7.5 7.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.13 6.49 6.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.26 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database