CHEMBL431074


SMILES Cc1ncc2c(n1)C1Oc3c(O)ccc4c3C13CCN(C)C(C4)C3(O)C2
InChIKey OCIKRCLBDNYUFW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 351.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.62 7.62 7.62 ChEMBL
κ OPRK Human Opioid A pKi 7.16 7.16 7.16 ChEMBL
μ OPRM Human Opioid A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.02 7.02 7.02 ChEMBL
κ OPRK Human Opioid A pEC50 5.56 5.56 5.56 ChEMBL
μ OPRM Human Opioid A pEC50 7.14 7.14 7.14 ChEMBL