CHEMBL435746


SMILES C[C@H]1CN2C[C@H](Cc3ccccc3)NC[C@H]2C[C@@]1(C)c1cccc(O)c1
InChIKey FYKCIOAYMLTGHC-MDFGKDKASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.44 7.44 7.44 ChEMBL
κ OPRK Human Opioid A pKi 7.07 7.07 7.07 ChEMBL
μ OPRM Human Opioid A pKi 8.05 8.05 8.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 7.48 7.48 7.48 ChEMBL
κ OPRK Human Opioid A pIC50 7.8 7.8 7.8 ChEMBL
μ OPRM Human Opioid A pIC50 7.54 8.04 8.55 ChEMBL