CHEMBL1253632


SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
InChIKey HEVKQILECXRYNK-AMEOFWRWSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 13
Molecular weight (Da) 585.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 6.0 6.0 6.0 ChEMBL
μ OPRM Rat Opioid A pKi 7.24 7.41 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pEC50 6.07 6.07 6.07 ChEMBL
δ OPRD Mouse Opioid A pIC50 5.89 5.89 5.89 ChEMBL