CHEMBL4441457


SMILES CC[C@@H]1CN2CC[C@]3(Nc4cccc(-c5ccoc5)c4C3=O)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC
InChIKey NWOZMHXOJGIQFO-BHKYNAABSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 450.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 7.41 7.41 7.41 ChEMBL
μ OPRM Mouse Opioid A pKi 9.03 9.03 9.03 ChEMBL
δ OPRD Mouse Opioid A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 6.7 6.7 6.7 ChEMBL
μ OPRM Mouse Opioid A pEC50 8.82 8.82 8.82 ChEMBL
δ OPRD Mouse Opioid A pIC50 7.41 7.41 7.41 ChEMBL