CHEMBL445106


SMILES COc1cc(Br)c2c3c1C[C@H](N)C[C@@H]3CO2
InChIKey CLZKGXPLDDUCQZ-RNFRBKRXSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 283.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.58 6.58 6.59 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.05 7.63 8.22 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.62 7.25 7.89 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database