CHEMBL4453504


SMILES CC[C@@H]1CN2CC[C@]3(Nc4ccccc4C3=O)[C@@H]2C[C@@H]1/C(=C\OC)C(=O)OC
InChIKey ZGFZEUQTWZGDLW-GHINOQSISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 7.72 7.72 7.72 ChEMBL
μ OPRM Mouse Opioid A pKi 9.34 9.34 9.34 ChEMBL
δ OPRD Mouse Opioid A pKi 8.54 8.54 8.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 6.6 6.6 6.6 ChEMBL
μ OPRM Mouse Opioid A pEC50 8.85 8.85 8.85 ChEMBL
δ OPRD Mouse Opioid A pIC50 6.71 6.71 6.71 ChEMBL