CHEMBL1256171


SMILES O=C(NCCCCN1CCN(c2cc3ccc2CCc2ccc(cc2)CC3)CC1)c1cc2ccc1CCc1ccc(cc1)CC2
InChIKey MAMYYNBMHYGSHM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 597.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.11 5.11 5.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.77 6.77 6.77 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.32 7.41 7.5 ChEMBL
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.09 5.09 5.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database