CHEMBL4471669


SMILES CCCCN1CCN(c2cccc(CC)c2Cl)CC1
InChIKey YTGXGXKZORFSRT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 280.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.44 9.44 9.44 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.43 7.43 7.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.53 8.53 8.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 7.2 7.2 7.2 ChEMBL
D3 DRD3 Human Dopamine A pEC50 6.23 6.23 6.23 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.32 7.32 7.32 ChEMBL