CHEMBL4514319


SMILES Cc1cc(O)c(Cl)c(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey PDKCGZGFRIANAD-LJWNLINESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 5
Rotatable bonds 12
Molecular weight (Da) 633.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.05 6.05 6.05 ChEMBL
κ OPRK Human Opioid A pKi 7.43 7.43 7.43 ChEMBL
μ OPRM Human Opioid A pKi 9.59 9.59 9.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 9.21 9.21 9.21 ChEMBL