CHEMBL451543


SMILES CSc1ccc2c(c1)N(C[C@H](C)N)CC2
InChIKey MBDXWHFBIOEOHU-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 222.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 8.0 8.0 8.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.58 7.58 7.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.79 6.79 6.79 ChEMBL