CHEMBL4527124


SMILES Cc1cc(OCc2nc(N)nc(N3CCN(C)CC3)n2)ccc1Cl
InChIKey CCISGKKJVBOKKE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 348.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.23 5.23 5.23 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.45 5.45 5.45 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.91 5.91 5.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database