CHEMBL4531291


SMILES C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O
InChIKey XIDWPEYKZWKFNR-HPMMOBRVSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 8
Rotatable bonds 9
Molecular weight (Da) 929.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Mouse Melanocortin A pKd 5.4 5.4 5.4 ChEMBL
MC4 MC4R Mouse Melanocortin A pKd 6.0 6.0 6.0 ChEMBL
MC4 MC4R Human Melanocortin A pKd 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pIC50 4.92 4.92 4.92 ChEMBL
MC1 MSHR Mouse Melanocortin A pIC50 4.6 4.6 4.6 ChEMBL
MC3 MC3R Mouse Melanocortin A pIC50 4.82 4.82 4.82 ChEMBL
MC4 MC4R Mouse Melanocortin A pIC50 6.0 6.0 6.0 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 5.57 5.57 5.57 ChEMBL