CHEMBL4543685


SMILES CCc1cc(Cl)c(OC)c(N2CCN(C)CC2)c1
InChIKey HNMDMLNEALPPKX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 268.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.76 7.76 7.76 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.36 5.36 5.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 5.74 5.74 5.74 ChEMBL