CHEMBL4550633


SMILES COc1cccc(CN(NC(=O)NCCCN2CCN(c3ccccc3OC)CC2)c2ccc(F)cc2)c1
InChIKey LNBKOOVQBZWETK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 521.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.23 8.23 8.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.96 7.08 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database