CHEMBL455431


SMILES Cc1ccc([C@H](Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1
InChIKey QPFHUUXBBCZCOF-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pKi 7.85 7.85 7.85 ChEMBL
CXCR2 CXCR2 Human Chemokine A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR1 CXCR1 Human Chemokine A pIC50 6.84 6.84 6.84 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 7.68 7.68 7.68 ChEMBL