CHEMBL4560123


SMILES N=C(N)N(CCCCN1CCN(CCCCCCCOc2ccccc2)CC1)Cc1ccc([N+](=O)[O-])cc1
InChIKey SAZDSXKHNDLLLA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 17
Molecular weight (Da) 524.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Guinea pig Histamine A pKd 8.43 8.43 8.43 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 6.65 6.65 6.65 ChEMBL
H3 HRH3 Rat Histamine A pKi 7.8 7.8 7.8 ChEMBL
H4 HRH4 Human Histamine A pKi 5.92 5.92 5.92 ChEMBL
H3 HRH3 Human Histamine A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database