CHEMBL4560883


SMILES Cc1cc(Cl)ccc1OCc1nc(N)nc(N2CCN(C)CC2)n1
InChIKey HJUULADZDAQJAD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 348.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.82 4.82 4.82 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.36 5.36 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database