CHEMBL4562437


SMILES Cc1cccc(C)c1N1C(=O)[C@H](CC2CNc3ccccc32)NC2(CCN(C)CC2)C1=O
InChIKey FVVJBQFXISQDKF-BPARTEKVSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 432.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
μ OPRM Human Opioid A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database