CHEMBL4570411


SMILES O=C1c2ccc(F)cc2CC1CCN1CCCN(c2ccccn2)CC1
InChIKey KBSCSQTYTJMMEQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.23 7.24 7.24 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.72 6.72 6.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.6 5.62 5.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.23 7.23 7.23 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.05 6.07 6.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database