CHEMBL4582567


SMILES O=c1c(-c2ccc(F)cc2)c2n(c(=O)n1CCCCN1CCCC(c3c[nH]c4ccc(F)cc34)C1)CCCC2
InChIKey SIBAMPHTYYJSCQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 532.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database