CHEMBL4594673


SMILES CCOc1ccc(CN2CCc3ccccc3C2)cc1CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C
InChIKey OVWAZDSWAVPPTQ-NDEPHWFRSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 487.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.62 8.62 8.62 ChEMBL
κ OPRK Human Opioid A pKi 7.36 7.36 7.36 ChEMBL
μ OPRM Human Opioid A pKi 9.64 9.64 9.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 8.72 8.72 8.72 ChEMBL