CHEMBL4594692


SMILES CCN(CCCSc1nnc(-c2ccccc2)n1C)CC1CC1c1cc(F)ccc1OC
InChIKey CKXPAKSGYIPITQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 11
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.52 7.52 7.52 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.76 5.76 5.76 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.56 6.56 6.56 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.73 5.73 5.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database