CHEMBL4595148


SMILES CCCN(CCCCNC(=O)c1ccc2ccccc2c1)CC1CC1c1cc(F)ccc1OC
InChIKey MGGGAIHRQKOLDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 462.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.07 6.07 6.07 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.01 6.01 6.01 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.84 7.84 7.84 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database