CHEMBL4595728


SMILES CCOc1ccc(F)cc1C1CC1CN(CC)CCCSc1nnc(-c2ccccc2)n1C
InChIKey AKTVMLWMKKIHMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.8 5.8 5.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.0 7.0 7.0 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.94 5.94 5.94 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database