CHEMBL4596108


SMILES c1ccc(-c2ccc(OCCCCCN3CCCCCC3)cc2)cc1
InChIKey MGNUUPFOORCXCU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 337.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKd 6.14 6.14 6.14 ChEMBL
H4 HRH4 Human Histamine A pKi 4.66 4.66 4.66 ChEMBL
H1 HRH1 Human Histamine A pKi 5.9 5.9 5.9 ChEMBL
H3 HRH3 Human Histamine A pKi 7.47 7.47 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pIC50 8.04 8.04 8.04 ChEMBL