CHEMBL4597188


SMILES CCCN(CCCCNC(=O)c1ccc2ccccc2c1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl
InChIKey KFWJKLDOLDILRK-NOZRDPDXSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.68 7.68 7.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.94 5.94 5.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 5.45 5.45 5.45 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.0 7.0 7.0 ChEMBL