CHEMBL4597600


SMILES COc1ccc2c(c1)c(-c1[nH]c(N)nc1C)cn2S(=O)(=O)c1ccc2ccccc2c1
InChIKey KNJPQUOOYYJYMY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 432.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.63 5.63 5.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database