CHEMBL4598234


SMILES CCOc1ccc(CN(C)Cc2ccccc2)cc1CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C
InChIKey KPXGFGQGRVQEQZ-MHZLTWQESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 475.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.71 8.71 8.71 ChEMBL
κ OPRK Human Opioid A pKi 7.91 7.91 7.91 ChEMBL
μ OPRM Human Opioid A pKi 9.32 9.32 9.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 7.47 7.47 7.47 ChEMBL