CHEMBL1258452


SMILES CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1
InChIKey DZZIAERGLDKTBT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 320.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 5.9 5.9 5.9 ChEMBL
β1 ADRB1 Rat Adrenoceptors A pKi 5.36 5.36 5.36 ChEMBL
D3 DRD3 Rat Dopamine A pKi 5.2 5.2 5.2 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.62 8.62 8.62 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.25 5.25 5.25 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.37 5.37 5.37 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.39 5.39 5.39 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.0 6.0 6.0 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.59 5.59 5.59 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.96 5.96 5.96 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
H3 HRH3 Guinea pig Histamine A pKi 5.78 5.78 5.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database