PHENAZOCINE


SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1
InChIKey ZQHYKVKNPWDQSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.1 8.66 9.22 PDSP Ki database
μ OPRM Human Opioid A pKi 9.7 9.7 9.7 PDSP Ki database
δ OPRD Human Opioid A pKi 8.3 8.3 8.3 PDSP Ki database
κ OPRK Human Opioid A pKi 8.7 8.7 8.7 PDSP Ki database
κ OPRK Human Opioid A pKi 8.06 8.06 8.06 Drug Central
μ OPRM Human Opioid A pKi 8.01 8.01 8.01 Drug Central
δ OPRD Human Opioid A pKi 8.08 8.08 8.08 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 8.1 8.1 8.1 ChEMBL
κ OPRK Human Opioid A pIC50 6.92 6.92 6.92 ChEMBL
μ OPRM Mouse Opioid A pIC50 8.09 8.09 8.09 Drug Central