CHEMBL469815


SMILES NC(=O)c1ccc2c(c1O)[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(O)Cc1c([nH]c2ccccc12)C3
InChIKey SYDFANRJNFCVKV-GDKKVTFASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 10.6 10.6 10.6 ChEMBL
κ OPRK Human Opioid A pKi 9.09 9.09 9.09 ChEMBL
μ OPRM Human Opioid A pKi 9.29 9.29 9.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 10.1 10.1 10.1 ChEMBL
κ OPRK Human Opioid A pIC50 7.55 7.55 7.55 ChEMBL